Characterization of a putative hemagglutinin gene in the caprine model for brucellosis

Document Type

Article

Publication Date

9-13-2010

Abstract

With the completion of the genomic sequences of Brucella melitensis 16M and B. abortus 2308 and the vaccine strain RB51, a putative hemagglutinin gene was identified that is present in 16M and absent in B. abortus. The possibility of this hemagglutinin being a potential host specificity factor was evaluated via expression in trans in B. abortus 2308-QAE and RB51-QAE. Using the caprine brucellosis model, colonization and pathogenesis studies were performed to evaluate the strains. © 2010 Springer Science+Business Media B.V.

Publication Source (Journal or Book title)

NATO Science for Peace and Security Series A: Chemistry and Biology

First Page

99

Last Page

108

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